Innovative Attempts to Propagate EEHV Cell Culture
The ability to grow and propagate this virus in laboratory conditions is so critical for the progress of future research towards understanding the biology and pathology of this virus, as well as for any hoped for possibility of generating live attenuated vaccines that additional innovative approaches must be carried out as one of the top priority goals of EEHV research. This study will employ a variety of improved detection methods and alternative approaches beyond the simplistic standard ones.
Validation of the Effectiveness of Anti-Herpesvirus Inhibitors for EEHV Disease
This project will carry out sophisticated basic research experiments designed to answer which if any of the drugs are truly capable of stopping EEHV so that informed decisions can be made.
Disease Risk Analyses for Tuberculosis Detection and Prevalence in Elephants
Identification of risk factors and assessment of currently available diagnostic methods in U.S. elephants will provide information that can be used for making recommendations to minimize transmission and prevent infection. Improved interpretation of diagnostic tests, identification of risk factors associated with infection, and assessment of the current infection status of the U.S. elephant population will facilitate decision-making by elephant managers, veterinarians, and regulatory officials regarding movement, treatment, and management of elephants to prevent TB infection.
Investigating a Low Tech Method of Cryopreserving Elephant Sperm
Cryopreservation of semen for use with artificial insemination has the potential to be a valuable tool in the management of elephants. Unfortunately, post‐thaw motility of cryopreserved Asian elephant sperm is usually poor. This study will investigate the use of manual seeding to control ice crystal propagation and thawing at temperatures higher than 37C as a method of increasing post‐thaw sperm quality of cryopreserved Asian elephant sperm.